Nuclear trafficking of regulator of G protein signaling proteins and their roles in the nucleus. Progress in molecular biology and translational science. Elsevier, London, UK. Fisher, R. Expression of multiple splice variant forms of RGS6 in mouse ventricular myocytes. Samuel, I. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 10 10 , Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 10 7 , Regulators of G protein signaling function in zebrafish development.
Mayuzumi, D. Exacerbation of acute pancreatitis by combined cholinergic stimulation and duct obstruction. American journal of surgery, 5 , Chatterjee, T. Liu, Z.
Table of contents
Bile-pancreatic juice exclusion increases cholinergic M3 and CCK-A receptor expression and interleukin-6 production in ligation-induced acute pancreatitis. Berman, D. A functional polymorphism in RGS6 modulates the risk of bladder cancer. Cancer research, 64 18 , Cholinergic receptor induction and JNK activation in acute pancreatitis. The Journal of biological chemistry, 32 , Mild heat and proteotoxic stress promote unique subcellular trafficking and nucleolar accumulation of RGS6 and other RGS proteins.
Heat stress, proteotoxic stress and inhibition of rDNA transcription promote unique subcellular trafficking and nucleolar localization of RGS proteins. The Journal of biological chemistry, 40 , RGS12TS-S localizes at nuclear matrix-associated subnuclear structures and represses transcription: structural requirements for subnuclear targeting and transcriptional repression.
Molecular and cellular biology, 22 12 , Castro-Fernandez, C. Endocrinology, 4 , Digestive Diseases. Hou, J. Identification and characterization of a novel splice variant form of rat platelet-activating factor PAF receptor. RGS12TS-S is a nuclear matrix protein: structural requirements for its subnuclear organization, nuclear matrix association and transcriptional regulatory effects. Mallis, R. Crystal structure of S-glutathiolated carbonic anhydrase III. FEBS letters, 3 , Novel alternative splicing and nuclear localization of human RGS12 gene products.
The Journal of biological chemistry, 38 , Cytoplasmic, nuclear, and golgi localization of RGS proteins. Evidence for N-terminal and RGS domain sequences as intracellular targeting motifs. The Journal of biological chemistry, 31 , Identification of nuclear and intra-nuclear targeting domains of RGS Interaction of Gbeta5 with splice variant forms of human RGS6.
Molecular cloning and intracellular localization of novel human RGS6 variants: role of G protein gamma subunit-like GGL domain and Gbeta5 in intracellular localization. Melliti, K.
School of Biomedical Sciences - University of Queensland
Regulators of G protein signaling attenuate the G protein-mediated inhibition of N-type Ca channels. The Journal of general physiology, 1 , RGS12 promotes migration of Gialpha to the cell nucleus. RGS4 is a nucleo-cytoplasmic shuttle protein. Carlson, S. Molecular pharmacology, 53 3 , Cui, Q. Genomic organization, 5'-flanking region, and chromosomal localization of the human RGS3 gene. Genomics, 45 2 , A truncated form of RGS3 negatively regulates G protein-coupled receptor stimulation of adenylyl cyclase and phosphoinositide phospholipase C.
The Journal of biological chemistry, 24 , Genomic organization of the rat pituitary adenylate cyclase-activating polypeptide receptor gene. Alternative splicing within the 5'-untranslated region. A truncated form of RGS3 negatively regulates G protein-coupled receptor stimulation of MAP kinase, adenylyl cyclase and phosphoinositide phospholipase C.
Eapen, A. Genomic organization, 5'-flanking region and chromosomal localization of the human RGS3 gene. Molecular cloning of a novel variant of the pituitary adenylate cyclase-activating polypeptide PACAP receptor that stimulates calcium influx by activation of L-type calcium channels.
The Journal of biological chemistry, 50 , Thomas, C. Genomic organization and the 5' flanking region of the gamma subunit of the human amiloride-sensitive epithelial sodium channel. The Journal of biological chemistry, 42 , The third intracellular domain of the platelet-activating factor receptor is a critical determinant in receptor coupling to phosphoinositide phospholipase C-activating G proteins.
Studies using intracellular domain minigenes and receptor chimeras. Lack of constitutive activation or inactivation of the platelet-activating factor receptor by glutamate substitution of alanine Hlavaty, T.
Radiotherapy for head and neck malignancies is associated with increased salivary platelet-activating factor content. Intl J Radiation Oncology. Signal transduction by the rat platelet-activating factor PAF receptor: Studies using chimeric receptors and cellular expression of cytoplasmic domains of the receptor.
Structural organization of the rat pituitary adenylate cyclase activating polypeptide PACAP receptor gene: Evidence for alternative splicing in the 5'-untranslated region. Multiple affinity and guanine nucleotide sensitive forms of the calcitonin gene related peptide CGRP receptor. Canadian journal of physiology and pharmacology, 73 7 , Book Review: The Tachykinin Receptors. Buck Eds. Humana Press, Totowa, New Jersey.
Cloning the 5' flanking region and a regulatory intron of the amiloride-sensitive gamma human epithelial sodium channel gamma-hENaC gene.
American Society of Nephrology. Molecular cloning of cDNAs encoding full length and truncated forms of platelet-activating factor PAF receptor from rat liver: tissue distribution and functional analysis. Multiple affinity and guanine nucleotide-sensitive forms of the calcitonin gene-related peptide CGRP receptor. Use of PCR for isolation of neuropeptide receptor genes. Sarkaw Eds. Academic Press, Inc.
Original Research ARTICLE
Solubilization and characterization of a guanine nucleotide-sensitive form of the calcitonin gene-related peptide receptor. Molecular pharmacology, 43 2 , Identification and characterization of thromboxane A2 receptors in rat liver sinusoidal cells. Hines, K. Stimulation of glycogenolysis and platelet-activating factor PAF production during antigen-induced anaphylaxis in the perfused rat liver.
Regulation of hepatic glycogenolysis and vasoconstriction during antigen-induced anaphylaxis. The American journal of physiology, 5 Pt 1 , G Measurement of hepatic portal vein blood flow velocity in the rat using an intra-vascular doppler flow probe. Solubilization and characterization of a guanine nucleotide-sensitive form of the calcitonin gene-related peptide CGRP receptor from rat cerebellum. The thromboxane A2 analogue U increases hepatic portal pressure and blood glucose concentration in vivo.
Characterization and regulation of high affinity calcitonin gene-related peptide receptors in cultured neonatal rat cardiac myocytes. Endocrinology, 6 , Multiple affinity forms of the calcitonin gene-related peptide receptor in rat cerebellum.
Molecular pharmacology, 39 6 , Moy, J. Effects of nitric oxide on platelet-activating factor- and alpha-adrenergic-stimulated vasoconstriction and glycogenolysis in the perfused rat liver. The Journal of biological chemistry, 13 , PAF increases hepatic vascular resistance and glycogenolysis in vivo.
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The American journal of physiology, 3 Pt 1 , G Effects of nitric oxide NO on platelet-activating factor PAF - and alpha-adrenergic-stimulated vasoconstriction and glycogenolysis in the perfused rat liver. Nitric oxide NO inhibits antigen-stimulated increases in vasoconstriction and glycogenolysis in perfused livers derived from sensitized rats. Antigen-induced anaphylactic responses in liver: Putative role of platelet-activating factor.
Parsons, T. Nitrosocysteine inhibits agonist-mediated vasoconstriction in the isolated perfused rat liver. Kester, M. Biochimica et biophysica acta, 2 , Steinhelper, M. Beta 2-adrenergic agonist regulation of immune aggregate- and platelet-activating factor-stimulated hepatic metabolism. The Journal of biological chemistry, 19 , FEBS letters, , Hepatic actions of platelet-activating factor PAF in anesthetized rats. Blockade of this sensor mimics hypoglycaemia, thus augmenting glucagon secretion.
The patient may therefore have significant ketoacidosis without ketonuria, possibly delaying diagnosis if urinary ketones are used as a screening tool.